diff --git a/packages/vite/src/node/config.ts b/packages/vite/src/node/config.ts
index 17f7ba115..8bd49eef8 100644
--- a/packages/vite/src/node/config.ts
+++ b/packages/vite/src/node/config.ts
@@ -1762,20 +1762,6 @@ async function runConfigEnvironmentHook(
   }
 }
 
-export function getDepOptimizationOptions(
-  config: ResolvedConfig,
-  ssr: boolean,
-): DepOptimizationOptions {
-  return ssr ? config.ssr.optimizeDeps : config.optimizeDeps
-}
-export function isDepsOptimizerEnabled(
-  config: ResolvedConfig,
-  ssr: boolean,
-): boolean {
-  const optimizeDeps = getDepOptimizationOptions(config, ssr)
-  return !(optimizeDeps.noDiscovery && !optimizeDeps.include?.length)
-}
-
 function optimizeDepsDisabledBackwardCompatibility(
   resolved: ResolvedConfig,
   optimizeDeps: DepOptimizationOptions,
diff --git a/packages/vite/src/node/optimizer/index.ts b/packages/vite/src/node/optimizer/index.ts
index ac9a34fb2..9af9ba724 100644
--- a/packages/vite/src/node/optimizer/index.ts
+++ b/packages/vite/src/node/optimizer/index.ts
@@ -160,6 +160,15 @@ export interface DepOptimizationOptions {
   force?: boolean
 }
 
+export function isDepOptimizationEnabled(
+  optimizeDeps: DepOptimizationOptions,
+): boolean {
+  return (
+    !(optimizeDeps.disabled === true || optimizeDeps.disabled === 'dev') &&
+    !(optimizeDeps.noDiscovery && !optimizeDeps.include?.length)
+  )
+}
+
 // TODO: We first need to define if entries and force should be per-environment
 // export type ResolvedDepOptimizationOptions = Required<DepOptimizationOptions>
 
diff --git a/packages/vite/src/node/plugins/importAnalysis.ts b/packages/vite/src/node/plugins/importAnalysis.ts
index e897c7195..19ee2d352 100644
--- a/packages/vite/src/node/plugins/importAnalysis.ts
+++ b/packages/vite/src/node/plugins/importAnalysis.ts
@@ -51,7 +51,6 @@ import {
 } from '../utils'
 import { getFsUtils } from '../fsUtils'
 import { checkPublicFile } from '../publicDir'
-import { getDepOptimizationOptions } from '../config'
 import type { ResolvedConfig } from '../config'
 import type { Plugin } from '../plugin'
 import type { DevEnvironment } from '../server/environment'
@@ -277,20 +276,20 @@ export function importAnalysisPlugin(config: ResolvedConfig): Plugin {
 
         let importerFile = importer
 
-        const optimizeDeps = getDepOptimizationOptions(config, ssr)
-        if (moduleListContains(optimizeDeps?.exclude, url)) {
-          if (depsOptimizer) {
-            await depsOptimizer.scanProcessing
+        if (
+          depsOptimizer &&
+          moduleListContains(depsOptimizer.options.exclude, url)
+        ) {
+          await depsOptimizer.scanProcessing
 
-            // if the dependency encountered in the optimized file was excluded from the optimization
-            // the dependency needs to be resolved starting from the original source location of the optimized file
-            // because starting from node_modules/.vite will not find the dependency if it was not hoisted
-            // (that is, if it is under node_modules directory in the package source of the optimized file)
-            for (const optimizedModule of depsOptimizer.metadata.depInfoList) {
-              if (!optimizedModule.src) continue // Ignore chunks
-              if (optimizedModule.file === importerModule.file) {
-                importerFile = optimizedModule.src
-              }
+          // if the dependency encountered in the optimized file was excluded from the optimization
+          // the dependency needs to be resolved starting from the original source location of the optimized file
+          // because starting from node_modules/.vite will not find the dependency if it was not hoisted
+          // (that is, if it is under node_modules directory in the package source of the optimized file)
+          for (const optimizedModule of depsOptimizer.metadata.depInfoList) {
+            if (!optimizedModule.src) continue // Ignore chunks
+            if (optimizedModule.file === importerModule.file) {
+              importerFile = optimizedModule.src
             }
           }
         }
diff --git a/packages/vite/src/node/plugins/index.ts b/packages/vite/src/node/plugins/index.ts
index 6e3251181..1bd609d0a 100644
--- a/packages/vite/src/node/plugins/index.ts
+++ b/packages/vite/src/node/plugins/index.ts
@@ -1,7 +1,7 @@
 import aliasPlugin, { type ResolverFunction } from '@rollup/plugin-alias'
 import type { ObjectHook } from 'rollup'
 import type { PluginHookUtils, ResolvedConfig } from '../config'
-import { isDepsOptimizerEnabled } from '../config'
+import { isDepOptimizationEnabled } from '../optimizer'
 import type { HookHandler, Plugin, PluginWithRequiredHook } from '../plugin'
 import { watchPackageDataPlugin } from '../packages'
 import { getFsUtils } from '../fsUtils'
@@ -38,13 +38,14 @@ export async function resolvePlugins(
     ? await (await import('../build')).resolveBuildPlugins(config)
     : { pre: [], post: [] }
   const { modulePreload } = config.build
-  const depsOptimizerEnabled =
+  const depOptimizationEnabled =
     !isBuild &&
-    (isDepsOptimizerEnabled(config, false) ||
-      isDepsOptimizerEnabled(config, true))
+    Object.values(config.environments).some((environment) =>
+      isDepOptimizationEnabled(environment.dev.optimizeDeps),
+    )
 
   return [
-    depsOptimizerEnabled ? optimizedDepsPlugin(config) : null,
+    depOptimizationEnabled ? optimizedDepsPlugin(config) : null,
     isBuild ? metadataPlugin() : null,
     !isWorker ? watchPackageDataPlugin(config.packageCache) : null,
     preAliasPlugin(config),
diff --git a/packages/vite/src/node/server/environment.ts b/packages/vite/src/node/server/environment.ts
index e853644bd..3aa773e8d 100644
--- a/packages/vite/src/node/server/environment.ts
+++ b/packages/vite/src/node/server/environment.ts
@@ -12,12 +12,13 @@ import { getDefaultResolvedEnvironmentOptions } from '../config'
 import { mergeConfig, promiseWithResolvers } from '../utils'
 import type { FetchModuleOptions } from '../ssr/fetchModule'
 import { fetchModule } from '../ssr/fetchModule'
+import type { DepsOptimizer } from '../optimizer'
+import { isDepOptimizationEnabled } from '../optimizer'
 import {
   createDepsOptimizer,
   createExplicitDepsOptimizer,
 } from '../optimizer/optimizer'
 import { resolveEnvironmentPlugins } from '../plugin'
-import type { DepsOptimizer } from '../optimizer'
 import { EnvironmentModuleGraph } from './moduleGraph'
 import type { HMRChannel } from './hmr'
 import { createNoopHMRChannel, getShortName, updateModules } from './hmr'
@@ -139,11 +140,7 @@ export class DevEnvironment extends BaseEnvironment {
     const { optimizeDeps } = this.options.dev
     if (setup?.depsOptimizer) {
       this.depsOptimizer = setup?.depsOptimizer
-    } else if (
-      optimizeDeps?.disabled === true ||
-      optimizeDeps?.disabled === 'build' ||
-      (optimizeDeps?.noDiscovery && optimizeDeps?.include?.length === 0)
-    ) {
+    } else if (!isDepOptimizationEnabled(optimizeDeps)) {
       this.depsOptimizer = undefined
     } else {
       // We only support auto-discovery for the client environment, for all other