diff --git a/doc/api/cli.md b/doc/api/cli.md
index 0d2e28d22ec..755b961fdeb 100644
--- a/doc/api/cli.md
+++ b/doc/api/cli.md
@@ -1091,6 +1091,20 @@ generated as part of the test runner output. If no tests are run, a coverage
 report is not generated. See the documentation on
 [collecting code coverage from tests][] for more details.
 
+### `--experimental-test-isolation=mode`
+
+<!-- YAML
+added: REPLACEME
+-->
+
+> Stability: 1.0 - Early development
+
+Configures the type of test isolation used in the test runner. When `mode` is
+`'process'`, each test file is run in a separate child process. When `mode` is
+`'none'`, all test files run in the same process as the test runner. The default
+isolation mode is `'process'`. This flag is ignored if the `--test` flag is not
+present. See the [test runner execution model][] section for more information.
+
 ### `--experimental-test-module-mocks`
 
 <!-- YAML
@@ -2196,7 +2210,9 @@ added:
 -->
 
 The maximum number of test files that the test runner CLI will execute
-concurrently. The default value is `os.availableParallelism() - 1`.
+concurrently. If `--experimental-test-isolation` is set to `'none'`, this flag
+is ignored and concurrency is one. Otherwise, concurrency defaults to
+`os.availableParallelism() - 1`.
 
 ### `--test-coverage-exclude`
 
@@ -2361,7 +2377,7 @@ added: v22.3.0
 
 > Stability: 1.0 - Early development
 
-Regenerates the snapshot file used by the test runner for [snapshot testing][].
+Regenerates the snapshot files used by the test runner for [snapshot testing][].
 Node.js must be started with the `--experimental-test-snapshots` flag in order
 to use this functionality.
 
@@ -3534,6 +3550,7 @@ node --stack-trace-limit=12 -p -e "Error.stackTraceLimit" # prints 12
 [snapshot testing]: test.md#snapshot-testing
 [syntax detection]: packages.md#syntax-detection
 [test reporters]: test.md#test-reporters
+[test runner execution model]: test.md#test-runner-execution-model
 [timezone IDs]: https://en.wikipedia.org/wiki/List_of_tz_database_time_zones
 [tracking issue for user-land snapshots]: https://github.com/nodejs/node/issues/44014
 [ways that `TZ` is handled in other environments]: https://www.gnu.org/software/libc/manual/html_node/TZ-Variable.html
diff --git a/doc/api/test.md b/doc/api/test.md
index 60eeb51c954..cbfc9db94bb 100644
--- a/doc/api/test.md
+++ b/doc/api/test.md
@@ -445,18 +445,26 @@ in the [test runner execution model][] section.
 
 ### Test runner execution model
 
-Each matching test file is executed in a separate child process. The maximum
-number of child processes running at any time is controlled by the
-[`--test-concurrency`][] flag. If the child process finishes with an exit code
-of 0, the test is considered passing. Otherwise, the test is considered to be a
-failure. Test files must be executable by Node.js, but are not required to use
-the `node:test` module internally.
+When process-level test isolation is enabled, each matching test file is
+executed in a separate child process. The maximum number of child processes
+running at any time is controlled by the [`--test-concurrency`][] flag. If the
+child process finishes with an exit code of 0, the test is considered passing.
+Otherwise, the test is considered to be a failure. Test files must be executable
+by Node.js, but are not required to use the `node:test` module internally.
 
 Each test file is executed as if it was a regular script. That is, if the test
 file itself uses `node:test` to define tests, all of those tests will be
 executed within a single application thread, regardless of the value of the
 `concurrency` option of [`test()`][].
 
+When process-level test isolation is disabled, each matching test file is
+imported into the test runner process. Once all test files have been loaded, the
+top level tests are executed with a concurrency of one. Because the test files
+are all run within the same context, it is possible for tests to interact with
+each other in ways that are not possible when isolation is enabled. For example,
+if a test relies on global state, it is possible for that state to be modified
+by a test originating from another file.
+
 ## Collecting code coverage
 
 > Stability: 1 - Experimental
@@ -933,7 +941,7 @@ the [`--experimental-test-snapshots`][] command-line flag.
 Snapshot files are generated by starting Node.js with the
 [`--test-update-snapshots`][] command-line flag. A separate snapshot file is
 generated for each test file. By default, the snapshot file has the same name
-as `process.argv[1]` with a `.snapshot` file extension. This behavior can be
+as the test file with a `.snapshot` file extension. This behavior can be
 configured using the `snapshot.setResolveSnapshotPath()` function. Each
 snapshot assertion corresponds to an export in the snapshot file.
 
@@ -1239,6 +1247,9 @@ added:
   - v18.9.0
   - v16.19.0
 changes:
+  - version: REPLACEME
+    pr-url: https://github.com/nodejs/node/pull/53927
+    description: Added the `isolation` option.
   - version: v22.6.0
     pr-url: https://github.com/nodejs/node/pull/53866
     description: Added the `globPatterns` option.
@@ -1274,8 +1285,13 @@ changes:
   * `inspectPort` {number|Function} Sets inspector port of test child process.
     This can be a number, or a function that takes no arguments and returns a
     number. If a nullish value is provided, each process gets its own port,
-    incremented from the primary's `process.debugPort`.
-    **Default:** `undefined`.
+    incremented from the primary's `process.debugPort`. This option is ignored
+    if the `isolation` option is set to `'none'` as no child processes are
+    spawned. **Default:** `undefined`.
+  * `isolation` {string} Configures the type of test isolation. If set to
+    `'process'`, each test file is run in a separate child process. If set to
+    `'none'`, all test files run in the current process. **Default:**
+    `'process'`.
   * `only`: {boolean} If truthy, the test context will only run tests that
     have the `only` option set
   * `setup` {Function} A function that accepts the `TestsStream` instance
@@ -1727,9 +1743,9 @@ added: v22.3.0
 
 * `fn` {Function} A function used to compute the location of the snapshot file.
   The function receives the path of the test file as its only argument. If the
-  `process.argv[1]` is not associated with a file (for example in the REPL),
-  the input is undefined. `fn()` must return a string specifying the location of
-  the snapshot file.
+  test is not associated with a file (for example in the REPL), the input is
+  undefined. `fn()` must return a string specifying the location of the snapshot
+  snapshot file.
 
 This function is used to customize the location of the snapshot file used for
 snapshot testing. By default, the snapshot filename is the same as the entry
diff --git a/doc/node.1 b/doc/node.1
index 5e809896321..6f333727ecf 100644
--- a/doc/node.1
+++ b/doc/node.1
@@ -185,6 +185,9 @@ Enable the experimental node:sqlite module.
 .It Fl -experimental-test-coverage
 Enable code coverage in the test runner.
 .
+.It Fl -experimental-test-isolation Ns = Ns Ar mode
+Configures the type of test isolation used in the test runner.
+.
 .It Fl -experimental-test-module-mocks
 Enable module mocking in the test runner.
 .
diff --git a/lib/internal/main/test_runner.js b/lib/internal/main/test_runner.js
index cc853da7388..b1f69b07771 100644
--- a/lib/internal/main/test_runner.js
+++ b/lib/internal/main/test_runner.js
@@ -21,7 +21,7 @@ markBootstrapComplete();
 
 const options = parseCommandLine();
 
-if (isUsingInspector()) {
+if (isUsingInspector() && options.isolation === 'process') {
   process.emitWarning('Using the inspector with --test forces running at a concurrency of 1. ' +
   'Use the inspectPort option to run with concurrency');
   options.concurrency = 1;
diff --git a/lib/internal/test_runner/harness.js b/lib/internal/test_runner/harness.js
index 3c56820cf4e..1bc6cddabd4 100644
--- a/lib/internal/test_runner/harness.js
+++ b/lib/internal/test_runner/harness.js
@@ -334,4 +334,5 @@ module.exports = {
   after: hook('after'),
   beforeEach: hook('beforeEach'),
   afterEach: hook('afterEach'),
+  startSubtestAfterBootstrap,
 };
diff --git a/lib/internal/test_runner/runner.js b/lib/internal/test_runner/runner.js
index a4874d5caea..b5431221b4e 100644
--- a/lib/internal/test_runner/runner.js
+++ b/lib/internal/test_runner/runner.js
@@ -11,6 +11,7 @@ const {
   ArrayPrototypeMap,
   ArrayPrototypePush,
   ArrayPrototypeShift,
+  ArrayPrototypeSlice,
   ArrayPrototypeSome,
   ArrayPrototypeSort,
   ObjectAssign,
@@ -24,6 +25,7 @@ const {
   StringPrototypeIndexOf,
   StringPrototypeSlice,
   StringPrototypeStartsWith,
+  Symbol,
   TypedArrayPrototypeGetLength,
   TypedArrayPrototypeSubarray,
 } = primordials;
@@ -44,18 +46,28 @@ const {
     ERR_TEST_FAILURE,
   },
 } = require('internal/errors');
+const esmLoader = require('internal/modules/esm/loader');
 const {
   validateArray,
   validateBoolean,
   validateFunction,
   validateObject,
+  validateOneOf,
   validateInteger,
 } = require('internal/validators');
 const { getInspectPort, isUsingInspector, isInspectorMessage } = require('internal/util/inspector');
 const { isRegExp } = require('internal/util/types');
-const { kEmptyObject } = require('internal/util');
+const { pathToFileURL } = require('internal/url');
+const {
+  createDeferredPromise,
+  getCWDURL,
+  kEmptyObject,
+} = require('internal/util');
 const { kEmitMessage } = require('internal/test_runner/tests_stream');
-const { createTestTree } = require('internal/test_runner/harness');
+const {
+  createTestTree,
+  startSubtestAfterBootstrap,
+} = require('internal/test_runner/harness');
 const {
   kAborted,
   kCancelledByParent,
@@ -77,7 +89,11 @@ const {
   triggerUncaughtException,
   exitCodes: { kGenericUserError },
 } = internalBinding('errors');
+let debug = require('internal/util/debuglog').debuglog('test_runner', (fn) => {
+  debug = fn;
+});
 
+const kIsolatedProcessName = Symbol('kIsolatedProcessName');
 const kFilterArgs = ['--test', '--experimental-test-coverage', '--watch'];
 const kFilterArgValues = ['--test-reporter', '--test-reporter-destination'];
 const kDiagnosticsFilterArgs = ['tests', 'suites', 'pass', 'fail', 'cancelled', 'skipped', 'todo', 'duration_ms'];
@@ -130,7 +146,12 @@ function getRunArgs(path, { forceExit, inspectPort, testNamePatterns, testSkipPa
   if (only === true) {
     ArrayPrototypePush(argv, '--test-only');
   }
-  ArrayPrototypePush(argv, path);
+
+  if (path === kIsolatedProcessName) {
+    ArrayPrototypePush(argv, '--test', ...ArrayPrototypeSlice(process.argv, 1));
+  } else {
+    ArrayPrototypePush(argv, path);
+  }
 
   return argv;
 }
@@ -326,7 +347,9 @@ class FileTest extends Test {
 
 function runTestFile(path, filesWatcher, opts) {
   const watchMode = filesWatcher != null;
-  const subtest = opts.root.createSubtest(FileTest, path, { __proto__: null, signal: opts.signal }, async (t) => {
+  const testPath = path === kIsolatedProcessName ? '' : path;
+  const testOpts = { __proto__: null, signal: opts.signal };
+  const subtest = opts.root.createSubtest(FileTest, testPath, testOpts, async (t) => {
     const args = getRunArgs(path, opts);
     const stdio = ['pipe', 'pipe', 'pipe'];
     const env = { __proto__: null, ...process.env, NODE_TEST_CONTEXT: 'child-v8' };
@@ -418,10 +441,23 @@ function watchFiles(testFiles, opts) {
   const filesWatcher = { __proto__: null, watcher, runningProcesses, runningSubtests };
   opts.root.harness.watching = true;
 
+  async function restartTestFile(file) {
+    const runningProcess = runningProcesses.get(file);
+    if (runningProcess) {
+      runningProcess.kill();
+      await once(runningProcess, 'exit');
+    }
+    if (!runningSubtests.size) {
+      // Reset the topLevel counter
+      opts.root.harness.counters.topLevel = 0;
+    }
+    await runningSubtests.get(file);
+    runningSubtests.set(file, runTestFile(file, filesWatcher, opts));
+  }
+
   watcher.on('changed', ({ owners, eventType }) => {
     if (!opts.hasFiles && eventType === 'rename') {
       const updatedTestFiles = createTestFileList(opts.globPatterns);
-
       const newFileName = ArrayPrototypeFind(updatedTestFiles, (x) => !ArrayPrototypeIncludes(testFiles, x));
       const previousFileName = ArrayPrototypeFind(testFiles, (x) => !ArrayPrototypeIncludes(updatedTestFiles, x));
 
@@ -439,25 +475,22 @@ function watchFiles(testFiles, opts) {
 
     }
 
-    watcher.unfilterFilesOwnedBy(owners);
-    PromisePrototypeThen(SafePromiseAllReturnVoid(testFiles, async (file) => {
-      if (!owners.has(file)) {
-        return;
-      }
-      const runningProcess = runningProcesses.get(file);
-      if (runningProcess) {
-        runningProcess.kill();
-        await once(runningProcess, 'exit');
-      }
-      if (!runningSubtests.size) {
-        // Reset the topLevel counter
-        opts.root.harness.counters.topLevel = 0;
-      }
-      await runningSubtests.get(file);
-      runningSubtests.set(file, runTestFile(file, filesWatcher, opts));
-    }, undefined, (error) => {
-      triggerUncaughtException(error, true /* fromPromise */);
-    }));
+    if (opts.isolation === 'none') {
+      PromisePrototypeThen(restartTestFile(kIsolatedProcessName), undefined, (error) => {
+        triggerUncaughtException(error, true /* fromPromise */);
+      });
+    } else {
+      watcher.unfilterFilesOwnedBy(owners);
+      PromisePrototypeThen(SafePromiseAllReturnVoid(testFiles, async (file) => {
+        if (!owners.has(file)) {
+          return;
+        }
+
+        await restartTestFile(file);
+      }, undefined, (error) => {
+        triggerUncaughtException(error, true /* fromPromise */);
+      }));
+    }
   });
   if (opts.signal) {
     kResistStopPropagation ??= require('internal/event_target').kResistStopPropagation;
@@ -485,6 +518,7 @@ function run(options = kEmptyObject) {
     files,
     forceExit,
     inspectPort,
+    isolation = 'process',
     watch,
     setup,
     only,
@@ -566,6 +600,7 @@ function run(options = kEmptyObject) {
       throw new ERR_INVALID_ARG_TYPE(name, ['string', 'RegExp'], value);
     });
   }
+  validateOneOf(isolation, 'options.isolation', ['process', 'none']);
 
   const rootTestOptions = { __proto__: null, concurrency, timeout, signal };
   const globalOptions = {
@@ -576,21 +611,16 @@ function run(options = kEmptyObject) {
     setup,  // This line can be removed when parseCommandLine() is removed here.
   };
   const root = createTestTree(rootTestOptions, globalOptions);
-
-  if (process.env.NODE_TEST_CONTEXT !== undefined) {
-    process.emitWarning('node:test run() is being called recursively within a test file. skipping running files.');
-    root.postRun();
-    return root.reporter;
-  }
   let testFiles = files ?? createTestFileList(globPatterns);
 
   if (shard) {
     testFiles = ArrayPrototypeFilter(testFiles, (_, index) => index % shard.total === shard.index - 1);
   }
 
-  let postRun = () => root.postRun();
-  let teardown = () => root.harness.teardown();
+  let teardown;
+  let postRun;
   let filesWatcher;
+  let runFiles;
   const opts = {
     __proto__: null,
     root,
@@ -602,21 +632,95 @@ function run(options = kEmptyObject) {
     globPatterns,
     only,
     forceExit,
+    isolation,
   };
-  if (watch) {
-    filesWatcher = watchFiles(testFiles, opts);
-    postRun = undefined;
-    teardown = undefined;
+
+  if (isolation === 'process') {
+    if (process.env.NODE_TEST_CONTEXT !== undefined) {
+      process.emitWarning('node:test run() is being called recursively within a test file. skipping running files.');
+      root.postRun();
+      return root.reporter;
+    }
+
+    if (watch) {
+      filesWatcher = watchFiles(testFiles, opts);
+    } else {
+      postRun = () => root.postRun();
+      teardown = () => root.harness.teardown();
+    }
+
+    runFiles = () => {
+      root.harness.bootstrapPromise = null;
+      root.harness.buildPromise = null;
+      return SafePromiseAllSettledReturnVoid(testFiles, (path) => {
+        const subtest = runTestFile(path, filesWatcher, opts);
+        filesWatcher?.runningSubtests.set(path, subtest);
+        return subtest;
+      });
+    };
+  } else if (isolation === 'none') {
+    if (watch) {
+      filesWatcher = watchFiles(testFiles, opts);
+      runFiles = async () => {
+        root.harness.bootstrapPromise = null;
+        root.harness.buildPromise = null;
+        const subtest = runTestFile(kIsolatedProcessName, filesWatcher, opts);
+        filesWatcher?.runningSubtests.set(kIsolatedProcessName, subtest);
+        return subtest;
+      };
+    } else {
+      runFiles = async () => {
+        const { promise, resolve: finishBootstrap } = createDeferredPromise();
+
+        await root.runInAsyncScope(async () => {
+          const parentURL = getCWDURL().href;
+          const cascadedLoader = esmLoader.getOrInitializeCascadedLoader();
+          let topLevelTestCount = 0;
+
+          root.harness.bootstrapPromise = promise;
+
+          for (let i = 0; i < testFiles.length; ++i) {
+            const testFile = testFiles[i];
+            const fileURL = pathToFileURL(testFile);
+            const parent = i === 0 ? undefined : parentURL;
+            let threw = false;
+            let importError;
+
+            root.entryFile = resolve(testFile);
+            debug('loading test file:', fileURL.href);
+            try {
+              await cascadedLoader.import(fileURL, parent, { __proto__: null });
+            } catch (err) {
+              threw = true;
+              importError = err;
+            }
+
+            debug(
+              'loaded "%s": top level test count before = %d and after = %d',
+              testFile,
+              topLevelTestCount,
+              root.subtests.length,
+            );
+            if (topLevelTestCount === root.subtests.length) {
+              // This file had no tests in it. Add the placeholder test.
+              const subtest = root.createSubtest(Test, testFile);
+              if (threw) {
+                subtest.fail(importError);
+              }
+              startSubtestAfterBootstrap(subtest);
+            }
+
+            topLevelTestCount = root.subtests.length;
+          }
+        });
+
+        debug('beginning test execution');
+        root.entryFile = null;
+        finishBootstrap();
+        root.processPendingSubtests();
+      };
+    }
   }
-  const runFiles = () => {
-    root.harness.bootstrapPromise = null;
-    root.harness.buildPromise = null;
-    return SafePromiseAllSettledReturnVoid(testFiles, (path) => {
-      const subtest = runTestFile(path, filesWatcher, opts);
-      filesWatcher?.runningSubtests.set(path, subtest);
-      return subtest;
-    });
-  };
 
   const setupPromise = PromiseResolve(setup?.(root.reporter));
   PromisePrototypeThen(PromisePrototypeThen(PromisePrototypeThen(setupPromise, runFiles), postRun), teardown);
diff --git a/lib/internal/test_runner/utils.js b/lib/internal/test_runner/utils.js
index e6c421ff870..882eb50aa5d 100644
--- a/lib/internal/test_runner/utils.js
+++ b/lib/internal/test_runner/utils.js
@@ -195,11 +195,12 @@ function parseCommandLine() {
   let coverageExcludeGlobs;
   let coverageIncludeGlobs;
   let destinations;
-  let only;
+  let isolation;
+  let only = getOptionValue('--test-only');
   let reporters;
   let shard;
-  let testNamePatterns;
-  let testSkipPatterns;
+  let testNamePatterns = mapPatternFlagToRegExArray('--test-name-pattern');
+  let testSkipPatterns = mapPatternFlagToRegExArray('--test-skip-pattern');
   let timeout;
 
   if (isChildProcessV8) {
@@ -230,10 +231,17 @@ function parseCommandLine() {
   }
 
   if (isTestRunner) {
+    isolation = getOptionValue('--experimental-test-isolation');
     timeout = getOptionValue('--test-timeout') || Infinity;
-    concurrency = getOptionValue('--test-concurrency') || true;
-    only = false;
-    testNamePatterns = null;
+
+    if (isolation === 'none') {
+      concurrency = 1;
+    } else {
+      concurrency = getOptionValue('--test-concurrency') || true;
+      only = false;
+      testNamePatterns = null;
+      testSkipPatterns = null;
+    }
 
     const shardOption = getOptionValue('--test-shard');
     if (shardOption) {
@@ -290,6 +298,7 @@ function parseCommandLine() {
     coverageIncludeGlobs,
     destinations,
     forceExit,
+    isolation,
     only,
     reporters,
     setup,
@@ -305,6 +314,16 @@ function parseCommandLine() {
   return globalTestOptions;
 }
 
+function mapPatternFlagToRegExArray(flagName) {
+  const patterns = getOptionValue(flagName);
+
+  if (patterns?.length > 0) {
+    return ArrayPrototypeMap(patterns, (re) => convertStringToRegExp(re, flagName));
+  }
+
+  return null;
+}
+
 function countCompletedTest(test, harness = test.root.harness) {
   if (test.nesting === 0) {
     harness.counters.topLevel++;
diff --git a/src/env-inl.h b/src/env-inl.h
index 203841a25c1..08fe98e10b7 100644
--- a/src/env-inl.h
+++ b/src/env-inl.h
@@ -645,7 +645,8 @@ inline bool Environment::owns_inspector() const {
 
 inline bool Environment::should_create_inspector() const {
   return (flags_ & EnvironmentFlags::kNoCreateInspector) == 0 &&
-         !options_->test_runner && !options_->watch_mode;
+         !(options_->test_runner && options_->test_isolation == "process") &&
+         !options_->watch_mode;
 }
 
 inline bool Environment::should_wait_for_inspector_frontend() const {
diff --git a/src/node_options.cc b/src/node_options.cc
index 6c1ee44d958..f88495d0bbb 100644
--- a/src/node_options.cc
+++ b/src/node_options.cc
@@ -143,6 +143,18 @@ void EnvironmentOptions::CheckOptions(std::vector<std::string>* errors,
   }
 
   if (test_runner) {
+    if (test_isolation == "none") {
+      debug_options_.allow_attaching_debugger = true;
+    } else {
+      if (test_isolation != "process") {
+        errors->push_back("invalid value for --experimental-test-isolation");
+      }
+
+#ifndef ALLOW_ATTACHING_DEBUGGER_IN_TEST_RUNNER
+      debug_options_.allow_attaching_debugger = false;
+#endif
+    }
+
     if (syntax_check_only) {
       errors->push_back("either --test or --check can be used, not both");
     }
@@ -159,10 +171,6 @@ void EnvironmentOptions::CheckOptions(std::vector<std::string>* errors,
       errors->push_back(
           "--watch-path cannot be used in combination with --test");
     }
-
-#ifndef ALLOW_ATTACHING_DEBUGGER_IN_TEST_RUNNER
-    debug_options_.allow_attaching_debugger = false;
-#endif
   }
 
   if (watch_mode) {
@@ -650,6 +658,9 @@ EnvironmentOptionsParser::EnvironmentOptionsParser() {
   AddOption("--experimental-test-coverage",
             "enable code coverage in the test runner",
             &EnvironmentOptions::test_runner_coverage);
+  AddOption("--experimental-test-isolation",
+            "configures the type of test isolation used in the test runner",
+            &EnvironmentOptions::test_isolation);
   AddOption("--experimental-test-module-mocks",
             "enable module mocking in the test runner",
             &EnvironmentOptions::test_runner_module_mocks);
diff --git a/src/node_options.h b/src/node_options.h
index 52d57610ed1..e166b3c5fdf 100644
--- a/src/node_options.h
+++ b/src/node_options.h
@@ -191,6 +191,7 @@ class EnvironmentOptions : public Options {
   std::vector<std::string> test_reporter_destination;
   bool test_only = false;
   bool test_udp_no_try_send = false;
+  std::string test_isolation = "process";
   std::string test_shard;
   std::vector<std::string> test_skip_pattern;
   std::vector<std::string> coverage_include_pattern;
diff --git a/test/fixtures/test-runner/no-isolation/one.test.js b/test/fixtures/test-runner/no-isolation/one.test.js
new file mode 100644
index 00000000000..69e0485a371
--- /dev/null
+++ b/test/fixtures/test-runner/no-isolation/one.test.js
@@ -0,0 +1,32 @@
+'use strict';
+const { before, beforeEach, after, afterEach, test, suite } = require('node:test');
+
+globalThis.GLOBAL_ORDER = [];
+
+before(function() {
+  GLOBAL_ORDER.push(`before one: ${this.name}`);
+});
+
+beforeEach(function() {
+  GLOBAL_ORDER.push(`beforeEach one: ${this.name}`);
+});
+
+after(function() {
+  GLOBAL_ORDER.push(`after one: ${this.name}`);
+});
+
+afterEach(function() {
+  GLOBAL_ORDER.push(`afterEach one: ${this.name}`);
+});
+
+suite('suite one', function() {
+  GLOBAL_ORDER.push(this.name);
+
+  test('suite one - test', { only: true }, function() {
+    GLOBAL_ORDER.push(this.name);
+  });
+});
+
+test('test one', function() {
+  GLOBAL_ORDER.push(this.name);
+});
diff --git a/test/fixtures/test-runner/no-isolation/two.test.js b/test/fixtures/test-runner/no-isolation/two.test.js
new file mode 100644
index 00000000000..50ae6541ce1
--- /dev/null
+++ b/test/fixtures/test-runner/no-isolation/two.test.js
@@ -0,0 +1,30 @@
+'use strict';
+const { before, beforeEach, after, afterEach, test, suite } = require('node:test');
+
+before(function() {
+  GLOBAL_ORDER.push(`before two: ${this.name}`);
+});
+
+beforeEach(function() {
+  GLOBAL_ORDER.push(`beforeEach two: ${this.name}`);
+});
+
+after(function() {
+  GLOBAL_ORDER.push(`after two: ${this.name}`);
+});
+
+afterEach(function() {
+  GLOBAL_ORDER.push(`afterEach two: ${this.name}`);
+});
+
+suite('suite two', function() {
+  GLOBAL_ORDER.push(this.name);
+
+  before(function() {
+    GLOBAL_ORDER.push(`before suite two: ${this.name}`);
+  });
+
+  test('suite two - test', { only: true }, function() {
+    GLOBAL_ORDER.push(this.name);
+  });
+});
diff --git a/test/fixtures/test-runner/snapshots/unit-2.js b/test/fixtures/test-runner/snapshots/unit-2.js
new file mode 100644
index 00000000000..311378b2810
--- /dev/null
+++ b/test/fixtures/test-runner/snapshots/unit-2.js
@@ -0,0 +1,11 @@
+'use strict';
+const { snapshot, test } = require('node:test');
+const { basename, join } = require('node:path');
+
+snapshot.setResolveSnapshotPath((testFile) => {
+  return join(process.cwd(), `${basename(testFile)}.snapshot`);
+});
+
+test('has a snapshot', (t) => {
+  t.assert.snapshot('a snapshot from ' + __filename);
+});
diff --git a/test/parallel/test-runner-cli-concurrency.js b/test/parallel/test-runner-cli-concurrency.js
index fbabaf08e27..b2aa0ac6c3c 100644
--- a/test/parallel/test-runner-cli-concurrency.js
+++ b/test/parallel/test-runner-cli-concurrency.js
@@ -24,3 +24,17 @@ test('concurrency of two', async () => {
   const cp = spawnSync(process.execPath, args, { cwd, env });
   assert.match(cp.stderr.toString(), /concurrency: 2,/);
 });
+
+test('isolation=none uses a concurrency of one', async () => {
+  const args = ['--test', '--experimental-test-isolation=none'];
+  const cp = spawnSync(process.execPath, args, { cwd, env });
+  assert.match(cp.stderr.toString(), /concurrency: 1,/);
+});
+
+test('isolation=none overrides --test-concurrency', async () => {
+  const args = [
+    '--test', '--experimental-test-isolation=none', '--test-concurrency=2',
+  ];
+  const cp = spawnSync(process.execPath, args, { cwd, env });
+  assert.match(cp.stderr.toString(), /concurrency: 1,/);
+});
diff --git a/test/parallel/test-runner-cli-timeout.js b/test/parallel/test-runner-cli-timeout.js
index b8998d397fa..53a3e4ce7ea 100644
--- a/test/parallel/test-runner-cli-timeout.js
+++ b/test/parallel/test-runner-cli-timeout.js
@@ -18,3 +18,11 @@ test('timeout of 10ms', async () => {
   const cp = spawnSync(process.execPath, args, { cwd, env });
   assert.match(cp.stderr.toString(), /timeout: 10,/);
 });
+
+test('isolation=none uses the --test-timeout flag', async () => {
+  const args = [
+    '--test', '--experimental-test-isolation=none', '--test-timeout=10',
+  ];
+  const cp = spawnSync(process.execPath, args, { cwd, env });
+  assert.match(cp.stderr.toString(), /timeout: 10,/);
+});
diff --git a/test/parallel/test-runner-cli.js b/test/parallel/test-runner-cli.js
index f165a509c99..d2d2eea8809 100644
--- a/test/parallel/test-runner-cli.js
+++ b/test/parallel/test-runner-cli.js
@@ -7,92 +7,162 @@ const { join } = require('path');
 const fixtures = require('../common/fixtures');
 const testFixtures = fixtures.path('test-runner');
 
-{
-  // File not found.
-  const args = ['--test', 'a-random-file-that-does-not-exist.js'];
-  const child = spawnSync(process.execPath, args);
+for (const isolation of ['none', 'process']) {
+  {
+    // File not found.
+    const args = [
+      '--test',
+      `--experimental-test-isolation=${isolation}`,
+      'a-random-file-that-does-not-exist.js',
+    ];
+    const child = spawnSync(process.execPath, args);
 
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stdout.toString(), '');
-  assert.match(child.stderr.toString(), /^Could not find/);
-}
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stdout.toString(), '');
+    assert.match(child.stderr.toString(), /^Could not find/);
+  }
 
-{
-  // Default behavior. node_modules is ignored. Files that don't match the
-  // pattern are ignored except in test/ directories.
-  const args = ['--test'];
-  const child = spawnSync(process.execPath, args, { cwd: join(testFixtures, 'default-behavior') });
+  {
+    // Default behavior. node_modules is ignored. Files that don't match the
+    // pattern are ignored except in test/ directories.
+    const args = ['--test', `--experimental-test-isolation=${isolation}`];
+    const child = spawnSync(process.execPath, args, { cwd: join(testFixtures, 'default-behavior') });
 
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /ok 1 - this should pass/);
-  assert.match(stdout, /not ok 2 - this should fail/);
-  assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
-  assert.match(stdout, /ok 4 - this should pass/);
-  assert.match(stdout, /ok 5 - this should be skipped/);
-  assert.match(stdout, /ok 6 - this should be executed/);
-}
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+    const stdout = child.stdout.toString();
 
-{
-  // Same but with a prototype mutation in require scripts.
-  const args = ['--require', join(testFixtures, 'protoMutation.js'), '--test'];
-  const child = spawnSync(process.execPath, args, { cwd: join(testFixtures, 'default-behavior') });
+    assert.match(stdout, /ok 1 - this should pass/);
+    assert.match(stdout, /not ok 2 - this should fail/);
+    assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
+    assert.match(stdout, /ok 4 - this should pass/);
+    assert.match(stdout, /ok 5 - this should be skipped/);
+    assert.match(stdout, /ok 6 - this should be executed/);
+  }
 
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /ok 1 - this should pass/);
-  assert.match(stdout, /not ok 2 - this should fail/);
-  assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
-  assert.match(stdout, /ok 4 - this should pass/);
-  assert.match(stdout, /ok 5 - this should be skipped/);
-  assert.match(stdout, /ok 6 - this should be executed/);
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-}
+  {
+    // Same but with a prototype mutation in require scripts.
+    const args = [
+      '--require', join(testFixtures, 'protoMutation.js'),
+      '--test',
+      `--experimental-test-isolation=${isolation}`,
+    ];
+    const child = spawnSync(process.execPath, args, { cwd: join(testFixtures, 'default-behavior') });
 
-{
-  // User specified files that don't match the pattern are still run.
-  const args = ['--test', join(testFixtures, 'index.js')];
-  const child = spawnSync(process.execPath, args, { cwd: testFixtures });
+    const stdout = child.stdout.toString();
+    assert.match(stdout, /ok 1 - this should pass/);
+    assert.match(stdout, /not ok 2 - this should fail/);
+    assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
+    assert.match(stdout, /ok 4 - this should pass/);
+    assert.match(stdout, /ok 5 - this should be skipped/);
+    assert.match(stdout, /ok 6 - this should be executed/);
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+  }
 
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /not ok 1 - .+index\.js/);
-}
+  {
+    // User specified files that don't match the pattern are still run.
+    const args = [
+      '--test',
+      `--experimental-test-isolation=${isolation}`,
+      join(testFixtures, 'index.js'),
+    ];
+    const child = spawnSync(process.execPath, args, { cwd: testFixtures });
 
-{
-  // Searches node_modules if specified.
-  const args = ['--test', join(testFixtures, 'default-behavior/node_modules/*.js')];
-  const child = spawnSync(process.execPath, args);
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+    const stdout = child.stdout.toString();
+    assert.match(stdout, /not ok 1 - .+index\.js/);
+  }
 
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /not ok 1 - .+test-nm\.js/);
-}
+  {
+    // Searches node_modules if specified.
+    const args = [
+      '--test',
+      `--experimental-test-isolation=${isolation}`,
+      join(testFixtures, 'default-behavior/node_modules/*.js'),
+    ];
+    const child = spawnSync(process.execPath, args);
 
-{
-  // The current directory is used by default.
-  const args = ['--test'];
-  const options = { cwd: join(testFixtures, 'default-behavior') };
-  const child = spawnSync(process.execPath, args, options);
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+    const stdout = child.stdout.toString();
+    assert.match(stdout, /not ok 1 - .+test-nm\.js/);
+  }
 
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /ok 1 - this should pass/);
-  assert.match(stdout, /not ok 2 - this should fail/);
-  assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
-  assert.match(stdout, /ok 4 - this should pass/);
-  assert.match(stdout, /ok 5 - this should be skipped/);
-  assert.match(stdout, /ok 6 - this should be executed/);
+  {
+    // The current directory is used by default.
+    const args = ['--test', `--experimental-test-isolation=${isolation}`];
+    const options = { cwd: join(testFixtures, 'default-behavior') };
+    const child = spawnSync(process.execPath, args, options);
+
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+    const stdout = child.stdout.toString();
+    assert.match(stdout, /ok 1 - this should pass/);
+    assert.match(stdout, /not ok 2 - this should fail/);
+    assert.match(stdout, /ok 3 - subdir.+subdir_test\.js/);
+    assert.match(stdout, /ok 4 - this should pass/);
+    assert.match(stdout, /ok 5 - this should be skipped/);
+    assert.match(stdout, /ok 6 - this should be executed/);
+  }
+
+  {
+    // Test combined stream outputs
+    const args = [
+      '--test',
+      `--experimental-test-isolation=${isolation}`,
+      'test/fixtures/test-runner/default-behavior/index.test.js',
+      'test/fixtures/test-runner/nested.js',
+      'test/fixtures/test-runner/invalid-tap.js',
+    ];
+    const child = spawnSync(process.execPath, args);
+
+    assert.strictEqual(child.status, 1);
+    assert.strictEqual(child.signal, null);
+    assert.strictEqual(child.stderr.toString(), '');
+    const stdout = child.stdout.toString();
+    assert.match(stdout, /# Subtest: this should pass/);
+    assert.match(stdout, /ok 1 - this should pass/);
+    assert.match(stdout, / {2}---/);
+    assert.match(stdout, / {2}duration_ms: .*/);
+    assert.match(stdout, / {2}\.\.\./);
+
+    assert.match(stdout, /# Subtest: .+invalid-tap\.js/);
+    assert.match(stdout, /invalid tap output/);
+    assert.match(stdout, /ok 2 - .+invalid-tap\.js/);
+
+    assert.match(stdout, /# Subtest: level 0a/);
+    assert.match(stdout, / {4}# Subtest: level 1a/);
+    assert.match(stdout, / {4}ok 1 - level 1a/);
+    assert.match(stdout, / {4}# Subtest: level 1b/);
+    assert.match(stdout, / {4}not ok 2 - level 1b/);
+    assert.match(stdout, / {6}code: 'ERR_TEST_FAILURE'/);
+    assert.match(stdout, / {6}stack: |-'/);
+    assert.match(stdout, / {8}TestContext\.<anonymous> .*/);
+    assert.match(stdout, / {4}# Subtest: level 1c/);
+    assert.match(stdout, / {4}ok 3 - level 1c # SKIP aaa/);
+    assert.match(stdout, / {4}# Subtest: level 1d/);
+    assert.match(stdout, / {4}ok 4 - level 1d/);
+    assert.match(stdout, /not ok 3 - level 0a/);
+    assert.match(stdout, / {2}error: '1 subtest failed'/);
+    assert.match(stdout, /# Subtest: level 0b/);
+    assert.match(stdout, /not ok 4 - level 0b/);
+    assert.match(stdout, / {2}error: 'level 0b error'/);
+    assert.match(stdout, /# tests 8/);
+    assert.match(stdout, /# suites 0/);
+    assert.match(stdout, /# pass 4/);
+    assert.match(stdout, /# fail 3/);
+    assert.match(stdout, /# cancelled 0/);
+    assert.match(stdout, /# skipped 1/);
+    assert.match(stdout, /# todo 0/);
+  }
 }
 
 {
@@ -115,57 +185,6 @@ const testFixtures = fixtures.path('test-runner');
   }
 }
 
-{
-  // Test combined stream outputs
-  const args = [
-    '--test',
-    'test/fixtures/test-runner/default-behavior/index.test.js',
-    'test/fixtures/test-runner/nested.js',
-    'test/fixtures/test-runner/invalid-tap.js',
-  ];
-  const child = spawnSync(process.execPath, args);
-
-
-  assert.strictEqual(child.status, 1);
-  assert.strictEqual(child.signal, null);
-  assert.strictEqual(child.stderr.toString(), '');
-  const stdout = child.stdout.toString();
-  assert.match(stdout, /# Subtest: this should pass/);
-  assert.match(stdout, /ok 1 - this should pass/);
-  assert.match(stdout, / {2}---/);
-  assert.match(stdout, / {2}duration_ms: .*/);
-  assert.match(stdout, / {2}\.\.\./);
-
-  assert.match(stdout, /# Subtest: .+invalid-tap\.js/);
-  assert.match(stdout, /# invalid tap output/);
-  assert.match(stdout, /ok 2 - .+invalid-tap\.js/);
-
-  assert.match(stdout, /# Subtest: level 0a/);
-  assert.match(stdout, / {4}# Subtest: level 1a/);
-  assert.match(stdout, / {4}ok 1 - level 1a/);
-  assert.match(stdout, / {4}# Subtest: level 1b/);
-  assert.match(stdout, / {4}not ok 2 - level 1b/);
-  assert.match(stdout, / {6}code: 'ERR_TEST_FAILURE'/);
-  assert.match(stdout, / {6}stack: |-'/);
-  assert.match(stdout, / {8}TestContext\.<anonymous> .*/);
-  assert.match(stdout, / {4}# Subtest: level 1c/);
-  assert.match(stdout, / {4}ok 3 - level 1c # SKIP aaa/);
-  assert.match(stdout, / {4}# Subtest: level 1d/);
-  assert.match(stdout, / {4}ok 4 - level 1d/);
-  assert.match(stdout, /not ok 3 - level 0a/);
-  assert.match(stdout, / {2}error: '1 subtest failed'/);
-  assert.match(stdout, /# Subtest: level 0b/);
-  assert.match(stdout, /not ok 4 - level 0b/);
-  assert.match(stdout, / {2}error: 'level 0b error'/);
-  assert.match(stdout, /# tests 8/);
-  assert.match(stdout, /# suites 0/);
-  assert.match(stdout, /# pass 4/);
-  assert.match(stdout, /# fail 3/);
-  assert.match(stdout, /# cancelled 0/);
-  assert.match(stdout, /# skipped 1/);
-  assert.match(stdout, /# todo 0/);
-}
-
 {
   // Test user logging in tests.
   const args = [
diff --git a/test/parallel/test-runner-coverage.js b/test/parallel/test-runner-coverage.js
index 8a6cb392de2..6cda6d2d1e0 100644
--- a/test/parallel/test-runner-coverage.js
+++ b/test/parallel/test-runner-coverage.js
@@ -187,6 +187,44 @@ test('coverage is combined for multiple processes', skipIfNoInspector, () => {
   assert.strictEqual(result.status, 0);
 });
 
+test('coverage works with isolation=none', skipIfNoInspector, () => {
+  // There is a bug in coverage calculation. The branch % in the common.js
+  // fixture is different depending on the test isolation mode. The 'none' mode
+  // is closer to what c8 reports here, so the bug is likely in the code that
+  // merges reports from different processes.
+  let report = [
+    '# start of coverage report',
+    '# -------------------------------------------------------------------',
+    '# file           | line % | branch % | funcs % | uncovered lines',
+    '# -------------------------------------------------------------------',
+    '# common.js      |  89.86 |    68.42 |  100.00 | 8 13-14 18 34-35 53',
+    '# first.test.js  |  83.33 |   100.00 |   50.00 | 5-6',
+    '# second.test.js | 100.00 |   100.00 |  100.00 | ',
+    '# third.test.js  | 100.00 |   100.00 |  100.00 | ',
+    '# -------------------------------------------------------------------',
+    '# all files      |  92.11 |    76.00 |   88.89 |',
+    '# -------------------------------------------------------------------',
+    '# end of coverage report',
+  ].join('\n');
+
+  if (common.isWindows) {
+    report = report.replaceAll('/', '\\');
+  }
+
+  const fixture = fixtures.path('v8-coverage', 'combined_coverage');
+  const args = [
+    '--test', '--experimental-test-coverage', '--test-reporter', 'tap', '--experimental-test-isolation=none',
+  ];
+  const result = spawnSync(process.execPath, args, {
+    env: { ...process.env, NODE_TEST_TMPDIR: tmpdir.path },
+    cwd: fixture,
+  });
+
+  assert.strictEqual(result.stderr.toString(), '');
+  assert(result.stdout.toString().includes(report));
+  assert.strictEqual(result.status, 0);
+});
+
 test('coverage reports on lines, functions, and branches', skipIfNoInspector, async (t) => {
   const fixture = fixtures.path('test-runner', 'coverage.js');
   const child = spawnSync(process.execPath,
diff --git a/test/parallel/test-runner-extraneous-async-activity.js b/test/parallel/test-runner-extraneous-async-activity.js
index 68db109b292..23f3194e02f 100644
--- a/test/parallel/test-runner-extraneous-async-activity.js
+++ b/test/parallel/test-runner-extraneous-async-activity.js
@@ -48,3 +48,21 @@ const { spawnSync } = require('child_process');
   assert.strictEqual(child.status, 1);
   assert.strictEqual(child.signal, null);
 }
+
+{
+  const child = spawnSync(process.execPath, [
+    '--test',
+    '--experimental-test-isolation=none',
+    fixtures.path('test-runner', 'async-error-in-test-hook.mjs'),
+  ]);
+  const stdout = child.stdout.toString();
+  assert.match(stdout, /^# Error: Test hook "before" at .+async-error-in-test-hook\.mjs:3:1 generated asynchronous activity after the test ended/m);
+  assert.match(stdout, /^# Error: Test hook "beforeEach" at .+async-error-in-test-hook\.mjs:9:1 generated asynchronous activity after the test ended/m);
+  assert.match(stdout, /^# Error: Test hook "after" at .+async-error-in-test-hook\.mjs:15:1 generated asynchronous activity after the test ended/m);
+  assert.match(stdout, /^# Error: Test hook "afterEach" at .+async-error-in-test-hook\.mjs:21:1 generated asynchronous activity after the test ended/m);
+  assert.match(stdout, /^# pass 1$/m);
+  assert.match(stdout, /^# fail 0$/m);
+  assert.match(stdout, /^# cancelled 0$/m);
+  assert.strictEqual(child.status, 1);
+  assert.strictEqual(child.signal, null);
+}
diff --git a/test/parallel/test-runner-force-exit-failure.js b/test/parallel/test-runner-force-exit-failure.js
index 1fff8f30d7e..ce1f3208c5b 100644
--- a/test/parallel/test-runner-force-exit-failure.js
+++ b/test/parallel/test-runner-force-exit-failure.js
@@ -4,12 +4,21 @@ const { match, doesNotMatch, strictEqual } = require('node:assert');
 const { spawnSync } = require('node:child_process');
 const fixtures = require('../common/fixtures');
 const fixture = fixtures.path('test-runner/throws_sync_and_async.js');
-const r = spawnSync(process.execPath, ['--test', '--test-force-exit', fixture]);
 
-strictEqual(r.status, 1);
-strictEqual(r.signal, null);
-strictEqual(r.stderr.toString(), '');
+for (const isolation of ['none', 'process']) {
+  const args = [
+    '--test',
+    '--test-force-exit',
+    `--experimental-test-isolation=${isolation}`,
+    fixture,
+  ];
+  const r = spawnSync(process.execPath, args);
 
-const stdout = r.stdout.toString();
-match(stdout, /error: 'fails'/);
-doesNotMatch(stdout, /this should not have a chance to be thrown/);
+  strictEqual(r.status, 1);
+  strictEqual(r.signal, null);
+  strictEqual(r.stderr.toString(), '');
+
+  const stdout = r.stdout.toString();
+  match(stdout, /error: 'fails'/);
+  doesNotMatch(stdout, /this should not have a chance to be thrown/);
+}
diff --git a/test/parallel/test-runner-no-isolation-filtering.js b/test/parallel/test-runner-no-isolation-filtering.js
new file mode 100644
index 00000000000..f8fba1cbfff
--- /dev/null
+++ b/test/parallel/test-runner-no-isolation-filtering.js
@@ -0,0 +1,69 @@
+'use strict';
+require('../common');
+const fixtures = require('../common/fixtures');
+const assert = require('node:assert');
+const { spawnSync } = require('node:child_process');
+const { test } = require('node:test');
+
+const fixture1 = fixtures.path('test-runner', 'no-isolation', 'one.test.js');
+const fixture2 = fixtures.path('test-runner', 'no-isolation', 'two.test.js');
+
+test('works with --test-only', () => {
+  const args = [
+    '--test',
+    '--experimental-test-isolation=none',
+    '--test-only',
+    fixture1,
+    fixture2,
+  ];
+  const child = spawnSync(process.execPath, args);
+  const stdout = child.stdout.toString();
+
+  assert.strictEqual(child.status, 0);
+  assert.strictEqual(child.signal, null);
+  assert.match(stdout, /# tests 2/);
+  assert.match(stdout, /# suites 2/);
+  assert.match(stdout, /# pass 2/);
+  assert.match(stdout, /ok 1 - suite one/);
+  assert.match(stdout, /ok 1 - suite one - test/);
+  assert.match(stdout, /ok 2 - suite two/);
+  assert.match(stdout, /ok 1 - suite two - test/);
+});
+
+test('works with --test-name-pattern', () => {
+  const args = [
+    '--test',
+    '--experimental-test-isolation=none',
+    '--test-name-pattern=/test one/',
+    fixture1,
+    fixture2,
+  ];
+  const child = spawnSync(process.execPath, args);
+  const stdout = child.stdout.toString();
+
+  assert.strictEqual(child.status, 0);
+  assert.strictEqual(child.signal, null);
+  assert.match(stdout, /# tests 1/);
+  assert.match(stdout, /# suites 0/);
+  assert.match(stdout, /# pass 1/);
+  assert.match(stdout, /ok 1 - test one/);
+});
+
+test('works with --test-skip-pattern', () => {
+  const args = [
+    '--test',
+    '--experimental-test-isolation=none',
+    '--test-skip-pattern=/one/',
+    fixture1,
+    fixture2,
+  ];
+  const child = spawnSync(process.execPath, args);
+  const stdout = child.stdout.toString();
+
+  assert.strictEqual(child.status, 0);
+  assert.strictEqual(child.signal, null);
+  assert.match(stdout, /# tests 1/);
+  assert.match(stdout, /# suites 1/);
+  assert.match(stdout, /# pass 1/);
+  assert.match(stdout, /ok 1 - suite two - test/);
+});
diff --git a/test/parallel/test-runner-no-isolation.mjs b/test/parallel/test-runner-no-isolation.mjs
new file mode 100644
index 00000000000..60b0c962e67
--- /dev/null
+++ b/test/parallel/test-runner-no-isolation.mjs
@@ -0,0 +1,47 @@
+import { allowGlobals, mustCall, mustNotCall } from '../common/index.mjs';
+import * as fixtures from '../common/fixtures.mjs';
+import { deepStrictEqual } from 'node:assert';
+import { run } from 'node:test';
+
+const stream = run({
+  files: [
+    fixtures.path('test-runner', 'no-isolation', 'one.test.js'),
+    fixtures.path('test-runner', 'no-isolation', 'two.test.js'),
+  ],
+  isolation: 'none',
+});
+
+stream.on('test:fail', mustNotCall());
+stream.on('test:pass', mustCall(5));
+// eslint-disable-next-line no-unused-vars
+for await (const _ of stream);
+allowGlobals(globalThis.GLOBAL_ORDER);
+deepStrictEqual(globalThis.GLOBAL_ORDER, [
+  'before one: <root>',
+  'suite one',
+  'before two: <root>',
+  'suite two',
+
+  'beforeEach one: suite one - test',
+  'beforeEach two: suite one - test',
+  'suite one - test',
+  'afterEach one: suite one - test',
+  'afterEach two: suite one - test',
+
+  'beforeEach one: test one',
+  'beforeEach two: test one',
+  'test one',
+  'afterEach one: test one',
+  'afterEach two: test one',
+
+  'before suite two: suite two',
+
+  'beforeEach one: suite two - test',
+  'beforeEach two: suite two - test',
+  'suite two - test',
+  'afterEach one: suite two - test',
+  'afterEach two: suite two - test',
+
+  'after one: <root>',
+  'after two: <root>',
+]);
diff --git a/test/parallel/test-runner-snapshot-tests.js b/test/parallel/test-runner-snapshot-tests.js
index e00019ef49d..62ebdd3cade 100644
--- a/test/parallel/test-runner-snapshot-tests.js
+++ b/test/parallel/test-runner-snapshot-tests.js
@@ -339,3 +339,75 @@ test('t.assert.snapshot()', async (t) => {
     t.assert.match(child.stdout, /fail 0/);
   });
 });
+
+test('snapshots from multiple files (isolation=none)', async (t) => {
+  tmpdir.refresh();
+
+  const fixture = fixtures.path('test-runner', 'snapshots', 'unit.js');
+  const fixture2 = fixtures.path('test-runner', 'snapshots', 'unit-2.js');
+
+  await t.test('fails prior to snapshot generation', async (t) => {
+    const args = [
+      '--test',
+      '--experimental-test-isolation=none',
+      '--experimental-test-snapshots',
+      fixture,
+      fixture2,
+    ];
+    const child = await common.spawnPromisified(
+      process.execPath,
+      args,
+      { cwd: tmpdir.path },
+    );
+
+    t.assert.strictEqual(child.code, 1);
+    t.assert.strictEqual(child.signal, null);
+    t.assert.match(child.stdout, /# tests 6/);
+    t.assert.match(child.stdout, /# pass 0/);
+    t.assert.match(child.stdout, /# fail 6/);
+    t.assert.match(child.stdout, /Missing snapshots/);
+  });
+
+  await t.test('passes when regenerating snapshots', async (t) => {
+    const args = [
+      '--test',
+      '--experimental-test-isolation=none',
+      '--experimental-test-snapshots',
+      '--test-update-snapshots',
+      fixture,
+      fixture2,
+    ];
+    const child = await common.spawnPromisified(
+      process.execPath,
+      args,
+      { cwd: tmpdir.path },
+    );
+
+    t.assert.strictEqual(child.code, 0);
+    t.assert.strictEqual(child.signal, null);
+    t.assert.match(child.stdout, /tests 6/);
+    t.assert.match(child.stdout, /pass 6/);
+    t.assert.match(child.stdout, /fail 0/);
+  });
+
+  await t.test('passes when snapshots exist', async (t) => {
+    const args = [
+      '--test',
+      '--experimental-test-isolation=none',
+      '--experimental-test-snapshots',
+      fixture,
+      fixture2,
+    ];
+    const child = await common.spawnPromisified(
+      process.execPath,
+      args,
+      { cwd: tmpdir.path },
+    );
+
+    t.assert.strictEqual(child.code, 0);
+    t.assert.strictEqual(child.signal, null);
+    t.assert.match(child.stdout, /tests 6/);
+    t.assert.match(child.stdout, /pass 6/);
+    t.assert.match(child.stdout, /fail 0/);
+  });
+});